Current Methods of Prevention of Aminoglycoside Ototoxicity in Patients with Pulmonary Tuberculosis
نویسندگان
چکیده
Contemporary publications on possible pharmaceutical treatment of ototoxic effect aminoglycosides have been analyzed. In this respect, substances with the antioxidant seem to be most promising. Their use in therapeutic doses is not accompanied by adverse reactions, and they do interfere antibacterial anti-tuberculosis drugs. Currently, mechanisms otoprotective action various antioxidants are being studied.
منابع مشابه
Prevention and modulation of aminoglycoside ototoxicity (Review).
More than 60 years after their isolation and characterization, aminoglycoside (AG) antibiotics remain powerful agents in the treatment of severe gram-negative, enterococcal or mycobacterial infections. However, the clinical use of AGs is hampered by nephrotoxicity and ototoxicity, which often develop as a consequence of prolonged courses of therapy, or of administration of increased doses of th...
متن کاملThe Incidence of Amikacin Ototoxicity in Multidrug-Resistant Tuberculosis Patients
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متن کاملThe Incidence of Amikacin Ototoxicity in Multidrug-Resistant Tuberculosis Patients
Amikacin has been shown to irreversibly suppressCochlear activity.The aim of this study is to assess the incidence of amikacinototoxicity in multidrug-resistant tuberculosis patients and riskfactors associated withthis ototoxicity.In this cross-sectional study, 41 patientswith multidrug-resistant tuberculosis (MDR-TB) were included.All patients received fixed dose of intravenous amikacin(500 mg...
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ژورنال
عنوان ژورنال: ?????????? ? ??????? ??????
سال: 2023
ISSN: ['2542-1506', '2075-1230']
DOI: https://doi.org/10.58838/2075-1230-2023-101-3-87-93